January 2019 - Wakunaga of America

Why Are B Vitamins So Important?

That’s right, I said eight B vitamins…not just one! B1, B2, B3, B5, B6, B7, B9, and B12, each perform unique and important functions in our bodies. These vitamins are essential because the body cannot make most of them, or they just cannot be made in large enough quantities by our bodies. These vitamins are water-soluble, which means that they are excreted from the body daily and must be replenished on a regular basis. Since B vitamins are already found in many foods to begin with, you are most likely not at risk for developing any type of vitamin B deficiency, as long as you follow a well-rounded diet. An interesting fact to note is that as you age, your ability to absorb B vitamins decreases and your appetite declines, making it difficult for some older people to get enough B vitamins through diet alone.

Health Benefits of Vitamin B

B vitamins are needed to carry out many different bodily functions. They help the metabolic system function, they help form red blood cells, and they even improve cognitive ability. But by far the most well know function of B vitamins is that they improve energy. B vitamins let your body convert food into energy, one if it’s most basic, yet most important functions. Many people attribute vitamin B to reduced fatigue, better cognitive performance, and even a boosted mood.

B vitamins will not cure mental health issues, but they may help improve symptoms of anxiety or depression. A study of 60 adults with depression showed that treatment with a B-complex vitamin for 60 days led to significant improvements in depression and anxiety symptoms, compared to a placebo.

Now that you know many of the benefits associated with taking B vitamins, let’s delve a little deeper into each of the eight vitamins.

Vitamin B1: Vitamin B1 is also known as thiamin, and it helps convert food into energy, plays a role in muscle contraction, and supports regular nervous system function. It also protects the immune system, and is also referred to as the “anti-stress” B vitamin. Some foods that contain this B vitamin are whole grains, spinach, kale, nuts, and red meat.

Vitamin B2: Vitamin B2 is also called riboflavin, and it helps your body break down and use the carbohydrates, fats, and proteins in your diet. It helps with red blood cell production, and also is important for body growth. Some foods that contain this B vitamin are beef, poultry, nuts, eggs, and fish.

Vitamin B3: Vitamin B3 is also known as niacin, and helps the digestive system, skin, and nerves to function. It can be found in poultry, legumes, fish, beef, and green vegetables.

Vitamin B5: Vitamin B5, aka pantothenic acid, is useful for our bodies because it helps break down fats and carbs for energy. It is also helpful because it enables our bodies to produce hormones. This B vitamin can be found in almost all foods groups, particularly egg yolk, avocados, and dairy products.

Vitamin B6: Vitamin B6 helps with over 100 cellular reactions in our bodies, and it is important because it helps the body metabolize amino acids from our food, build new red blood cells, and is involved in regulating sleep patterns. It can be found in meat, poultry, fish, bananas, peaches, and carrots.

Vitamin B7: Vitamin B7 is affectionately known as the “beauty vitamin,” as it helps boost hair, skin, and nails. This vitamin can be found in strawberries, egg yolks, nuts, and chicken.

Vitamin B9: Vitamin B9 is also known as folate, and it plays a huge role in fetal health and development because it helps develop the baby’s nervous system. This vitamin can be found in dates, avocados, and green leafy vegetables.

Vitamin B12: Vitamin B12 joins forces with vitamin B9 to produce red blood cells and iron to create its oxygen-carrying protein, called hemoglobin. This vitamin also helps maintain your central nervous system. It can be found in chicken, beef, pork, and clams.

If you would like to dabble in the world of B vitamins, and provide even greater support to your body for all of the functions it performs, look no further than Kyolic Formula 101. This formula contains Aged Garlic Extract, GABA, Vitamins B1, B6, and B12, and is designed for stress and fatigue relief.


  1. https://www.healthline.com/nutrition/vitamin-b-complex
  2. https://www.brainmdhealth.com/blog/how-to-get-all-8-b-vitamins/

This article is for informational purposes only. This article is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and should never be relied upon for specific medical advice.

Clinical Study – Kyolic AGE and Heart Health

High blood pressure has been linked to gut dysbiosis, with less microbial variety and lower levels of key bacteria that contribute to good health. Specifically, the abundance of the gut microbes, Firmicutes and Bacteroidetes, are associated with increased blood pressure in several models of hypertension. What’s more, gut dysbiosis has been found to increase chronic inflammation and the risk of cardiovascular events like heart attack and stroke.

In this groundbreaking new double-blind trial, 49 participants with uncontrolled hypertension were randomized to receive either 1.2g of AGE or a placebo for 12 weeks. Mean blood pressure was significantly reduced over the course of the trial, with a 10 mmHg drop in systolic blood pressure and a 5.4 mmHg decrease in diastolic blood pressure compared to the placebo. The researchers also noted that AGE lowered pulse pressure and arterial stiffness.

“The reduction in blood pressure was significant across the uncontrolled hypertensive patients,” said Ried. “This was seen in both the patients on standard hypertension medication and those taking no medication.” But she also notes that simply increasing the amount of garlic in your diet does not provide the same results gleaned from AGE since cooking destroys S-allyl cysteine, the bioavailable and active component responsible for these benefits.

Key Takeaways

But the most surprising finding during the trial was that AGE improved gut microbiota. This was evidenced by higher microbiota richness and diversity among those taking the supplement. A marked increase in two specific “good” bacteria species—Lactobacillus and Clostridia—was seen by the end of the study.

“While it wasn’t part of the study,” said Ried, “we also found the gut health of patients was maintained after the study.” This suggests that Kyolic AGE acts as a prebiotic, providing a sustained improvement in gut health.

Overall, these findings build upon earlier work by Ried and her team which found that taking just two capsules—or 480 mg—of AGE each day can effectively lower systolic blood pressure by up to 12 mgHg. Other studies have found that AGE, both alone and when combined with other nutrients such as Co-Q10, l-arginine, folic acid, vitamin B6 and vitamin B12, can improve a number of cardiovascular risk factors. Benefits include a reduction in coronary artery calcification, less arterial inflammation, improvement in blood vessel function, and a decrease in the amount of metabolically-active epicardial adipose tissue surrounding the heart. This important new investigation not only confirms that AGE effectively reduces blood pressure on its own, it also adds the improvement in gut dysbiosis to this list of cardiovascular benefits.

“This study is especially exciting as it offers evidence of new and unique ways that Kyolic Aged Garlic Extract benefits cardiovascular health,” says Jay Levy, Director of Sales for Wakunaga of America. “Because AGE is both safe and effective with few, if any, side effects compared to pharmaceuticals, it’s an easy addition to a healthy lifestyle for those concerned about supporting a healthy cardiovascular system.”

About the National Institute of Integrative Medicine: Located in Victoria, Australia, the NIIM is a not-for-profit organization that brings together education and research in Integrative Medicine, as well as facilitating its practice at the NIIM Wellness Clinic. With the support of local and international partners, the Institute conducts research into Complementary and Integrative Therapies, exploring innovative ideas and assessing the efficacy, toxicity and quality of Complementary and Alternative Medicines to expand the evidence base associated with Integrative Medicine.

This article is for informational purposes only. This article is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and should never be relied upon for specific medical advice.

Kyolic AGE vs. Fish Oil – which is better?

Traditional fish oil supplements come from several sources including salmon, sardines, and anchovies. The resulting oil from these sources contain two important omega-3s:  docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). Research shows that these two types of omega-3s are potent anti-inflammatory compounds that reduce triglycerides, improves cholesterol, lowers oxidative stress, and discourages platelets from sticking together inside arteries. There is also evidence that the DHA in fish oil modestly lowers blood pressure

While those are important heart-health benefits, AGE does all of that and more. A rich source of manganese, vitamin B6, vitamin C, and selenium, AGE is different from the pungent garlic cloves used for cooking. During a natural aging process that can take up to 20 months, the harsh unstable organosulfur properties in garlic are converted into stable bioavailable compounds with numerous health properties. In addition to being a powerful anti-inflammatory, studies have shown that AGE is high in antioxidants, including carboxylic acid and L-arginine, which play an important role in cardiovascular health.

Clinical Findings

Studies show that these beneficial properties translate to real cardiovascular benefits above and beyond those provided by fish oil. Findings in the journal Integrated Blood Pressure Control show that AGE effectively lowers both systolic and diastolic blood pressure in people with uncontrolled hypertension. After 12 weeks, researchers from the University of Adelaide and the National Institute of Integrative Medicine in Melbourne, Australia, found that 1.2g of AGE daily resulted in a 11.5 mmHg drop in their systolic blood pressure and a 6.3 mmHg reduction in their diastolic pressure. Arterial stiffness improved as well. Those taking the AGE also experienced modest improvements in an inflammatory marker known as CRP and cholesterol levels.

Other double-blind clinical trials conducted at the Harbor-University of California, Los Angeles Medical Center found that, not only did AGE lower blood pressure, it also reduced coronary artery calcification after a year of supplementation. In fact, AGE inhibited the progression of coronary artery calcification an average 1.78 fold compared to the placebo over the course of the study. AGE has also been shown to lower both triglycerides and bad LDL cholesterol while increasing good HDL cholesterol. What’s more, AGE lowers levels of homocysteine, an amino acid related to a high risk for heart disease. Together, these health improvements may prevent cardiac events like a stroke or heart attack.

Here’s a side-by-side comparison of the heart-healthy benefits provided by AGE and fish oil:


As the above chart shows, AGE’s broad-based benefits not only meet those provided by fish oil, it also targets additional important cardiovascular risks. Paired with a heart-smart diet and regular exercise, AGE is a comprehensive way to support a healthy cardiovascular system every day.

And remember, you can get the best of both worlds with Kyolic Omega-3! This formula contains 480mg of Aged Garlic Extract, Vitamin E, and odorless Omega-3 Fish oil with EPA and DHA, to support the body’s natural anti-inflammatory response. It’s truly a win-win for cardiovascular health!

This article is for informational purposes only. This article is not, nor is it intended to be, a substitute for professional medical advice, diagnosis, or treatment and should never be relied upon for specific medical advice.